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In situ hybridization and mapping of HCV virus in different patients. a: negative control with no traces of infected hepatocytes. Distribution of infected cells (arrow) in patients with 1.8 × 10 4 genome copies/ml (b) and with 1.2 × 10 6 genome copies/ml (c) in serum. d: General view of a single frame capture to show the distribution of the infection. e: Visualization of the infection in a single hepatocyte.
