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. 1999 Jun;154(6):1849–1855. doi: 10.1016/S0002-9440(10)65442-9

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Copyright © 1999, American Society for Investigative Pathology

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Figure 3. — Loss of heterozygosity (LOH) analysis in representative tumors. LOH (arrows) is observed at D5S592 in the ovarian tumor (O) of a pseudomyxoma case (PMP 14) but not in the matched appendiceal tumor (A), in an ovarian MLMP unassociated with PMP (OV 6), and in an appendiceal adenoma unassociated with PMP (APP 9). LOH at D18S51 is shown in another ovarian MLMP (OV 9). Other PMP (PMP 10) and ovarian MLMP (OV 8) tumors are informative for the D5S592 marker but show retention of both alleles. DNA from matched normal tissue (N) was compared with that from tumor tissue in each case.