Table 3.
Molecular Findings on Microdissected Tissue
| Case 1 | Case 2 | Case 3 | ||||
|---|---|---|---|---|---|---|
| MCL | FL | SLL | FL | SLL | MCL | |
| CDRIII | R1 | R2 (R1) | R1 (R2) | R2 (R1) | (R1) | R1 |
| FR2 | n.a. | n.a. | R1 | n.a. | R2 | R1 (R2) |
| bcl-2 | − | R | −* | −* | −* | −* |
| bcl-1 | −* | −* | −* | −* | −* | −* |
FL, follicular lymphoma; MCL, mantle cell lymphoma; SLL, small lymphocytic lymphoma; R, clonal IgH or bcl-2 rearrangement, respectively. The numbers in parentheses indicate the presence of a weaker and inconsistent product identical in sequence to the rearrangement of the other tumor part.
n.a., not amplified.
*Performed on DNA extracted from whole, undissected sections.