Table 2.
Sporadic Neoplasms Analyzed for STK11/LKB1 Mutations
Tumor type | Total number of samples | Number of samples analyzed in | Number of mutated samples | ||
---|---|---|---|---|---|
Homozygous deletion screening | LOH study | Sequencing | |||
Pancreatic adenocarcinoma | 100 | 100 | 92 | 30 | 4 |
Biliary adenocarcinoma | 16 | 16 | 0 | 0 | 1 |
Pancreatic cell lines | 11 | 11 | 11 | 9 | 0 |
Other carcinomas* | 19 | 19 | 0 | 0 | 0 |
*Primary carcinomas of the periampullary region, predominantly duodenal and ampullary cancers.