Figure 8.

Serum IgE concentrations in OVA immunized and challenged mice. Serum IgE was measured using a capture ELISA, as described in Materials and Methods. When compared with either unexposed (<400 ng/ml) or day 1 of aerosol ovalbumin exposure, significant increases in IgE levels were noted at days 5, 7, and 10 of acute exposure (**P ≤ 0.005; *P ≤ 0.05). Total serum IgE in mice subjected to chronic aerosol exposure (35 days) was not significantly different from mice exposed to OVA for 1 day. Data represent mean + SEM values for five to seven mice in each group.