Table 1.
Profile of Microsatellite Instable Gastric Cancers
Case | Markers* | Total no. of MSI loci | Rate of MSI (%)‡ | |||
---|---|---|---|---|---|---|
Mono (3)† | Tetra (12) | Tri (2) | Di (15) | |||
G6 | 2§ | 4 | 1 | 4 | 11 | 34 |
G15 | 2§ | 5 | 1 | 6 | 14 | 44 |
G22 | 3§ | 9 | 2 | 11 | 25 | 78 |
G30 | 0 | 2 | 0 | 2 | 4 | 13 |
G38 | 3§ | 5 | 1 | 3 | 13 | 41 |
G49 | 0 | 2 | 0 | 1 | 3 | 9 |
G52 | 0 | 0 | 0 | 1 | 1 | 3 |
G56 | 0 | 2 | 0 | 1 | 3 | 9 |
G59 | 0 | 2 | 0 | 3 | 5 | 16 |
G61 | 3§ | 2 | 1 | 9 | 15 | 47 |
G63 | 1 | 2 | 0 | 0 | 3 | 9 |
G65 | 3§ | 6 | 1 | 7 | 17 | 53 |
G99 | 1 | 0 | 0 | 2 | 3 | 9 |
G106 | 3§ | 7 | 0 | 4 | 14 | 44 |
G111 | 0 | 0 | 0 | 2 | 2 | 6 |
G119 | 0 | 2 | 0 | 2 | 4 | 13 |
G134 | 3§ | 7 | 1 | 7 | 18 | 56 |
G135 | 3§ | 6 | 0 | 9 | 18 | 56 |
G165 | 3§ | 8 | 1 | 8 | 20 | 63 |
*Number of microsatellite markers analyzed in parentheses. Tetra, Tetranucleotide repeat; Tri, trinucleotide repeat; Di, dinucleotide repeat; Mono, mononucleotide.
†BAT-26, BAT-25, and TGF-beta RII mononucleotide repeats analyzed.
‡The rate of MSI is the proportion of instable loci observed compared to the total number of loci examined (n = 32).
§Bat-26 locus instability.