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. 1999 Jul;155(1):235–245. doi: 10.1016/S0002-9440(10)65117-6

Figure 5.

Figure 5.

Heterogeneity of absent 15-LOX-2 immunostaining in prostate tumors. Immunostained entire whole-mount sections or right and/or left halves from four representative cases are outlined, with posterior toward top of figure. Benign glands stained uniformly, and stroma was negative as described in Results. Shaded outlines correspond only to actual tumor portions, with positive staining in dark gray and absent immunostaining areas in lighter shade. Numbers correspond to Gleason pattern of indicated areas (in tumors with more than one pattern). A through C correspond to cases A through C in Figure 3 ▶ (in which portions were also examined by HPLC assay). A: Gleason 3 + 4 = 7, overall 44.2% 15-LOX-2 negative. B: Gleason 4 + 3 = 7, overall 60.6% 15-LOX-2 negative. C: Gleason 3 + 3 = 6, overall 40% 15-LOX-2 negative. D: Gleason 3 + 3 = 6, overall 45% 15-LOX-2 negative.