Table 2.

Multipoint linkage analysis ordered by number of tagSNPs for the chromosome 21 region.

	# of SNPs	LOD score (p-value) simulated trait (chromosome 21) rs2835626	LOD Score (p-value) simulated trait (chromosome 20) tsc0041859	Mean information content
SNPtagger/HTSNP a	4	11.44 (<0.00001)	0.03 (0.4)	0.58
Nyholt	5	11.70 (<0.00001)	0.17 (0.2)	0.60
TagSNP	5	12.03 (<0.00001)	0.15 (0.2)	0.60
Haploview	6	12.42(<0.00001)	0.30 (0.12)	0.62
HB Finder	7	12.63 (<0.00001)	0.80 (0.03)	0.61
Mengb	8	13.27 (<0.00001)	1.08 (0.013)	0.60
All SNPs	17	13.50(<0.00001)	0.86 (0.02)	0.69

^aBold, program included the simulated trait on chromosome 21.

^bBlack, program _______________________________.