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In situ hybridization with the MMP-13 specific [35S]-labeled RNA probe in Crohn’s disease and a tonsillar squamous cell carcinoma. A clear autoradiographic signal is seen in few submucosal mesenchymal cells in Crohn’s disease (A), whereas a very intense signal is found in the peritumoral mesenchymal cells in the squamous cell carcinoma (B). Autoradiographic exposure time 36 days. Original magnifications, ×100 (A) and ×40 (B).
