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Semiquantitative evaluation of autoradiographic signals (silver grains) obtained with the MMP-1 probe in CC cases (closed bars) and in normal mucosa (hatched bars) as outlined in Figure 3 ▶ . In comparison to normal control mucosa, the number of MMP-1-expressing cells in general (A) and of cells with high specific transcript levels (B), and the average number of grains per labeled cell is (C) increased in CC. Note that these cells display a clustered distribution (Figure 5) ▶ .
