Table 1.
Summary of Clinical Information, Histopathological Diagnoses, and Morphometric Data
| Case | Age/sex | Diagnosis | Location | Collagenous band (μm) | Inflammation | IEL |
|---|---|---|---|---|---|---|
| 1 | 43 F | CC | 1 Ascending | 30.3 (7.5–50.0) | 1 | <5 |
| 2 Hepatic flexure | 38.0 (12.5–42.5) | 1 | <5 | |||
| 3 Transverse | 29.3 (7.5–40.0) | 1 | <5 | |||
| 4 Splenic flexure | 27.3 (15.0–40.0) | 1 | <5 | |||
| 5 Descending | 24.5 (7.5–50.0) | 1 | <5 | |||
| 6 Sigmoid | 36.7 (17.5–42.5) | 1 | <5 | |||
| 7 Rectum | 26.7 (10.0–50.0) | 1 | <5 | |||
| 2 | 81 F | CC | Splenic flexure | 12.7 (5.0–37.5) | 0–1 | <5 |
| 3 | 52 F | CC | Sigmoid | 18.8 (7.5–57.5) | 1 | <5 |
| 4 | 56 M | CC | Rectum | 16.7 (5.0–37.5) | 1 | <5 |
| 5 | 52 F | CC | 1 Appendix | 16.9 (10.0–75.0) | 1 | <5 |
| 2 Sigmoid | 11.1 (5.0–50.0) | 1 | <5 | |||
| 3 Rectum | 11.3 (5.0–12.5) | 1 | <5 | |||
| 6 | 51 F | CC | 1 Colon | 36.3 (5.0–50.0) | 1 | <5 |
| 2 Colon | 35.3 (12.5–42.5) | 1 | <5 | |||
| 3 Colon | 22.9 (10.0–45.0) | 1 | 5–10 | |||
| 4 Colon | 33.8 (17.5–50.0) | 1 | 5–10 | |||
| 7 | 55 F | CC | 1 Cecum | 38.3 (2.5–82.5) | 1 | <5 |
| 2 Ascending | 23.8 (2.5–50.0) | 1 | <5 | |||
| 3 Transverse | 44.2 (20.0–65.0) | 1 | <5 | |||
| 4 Descending | 37.7 (12.5–50.0) | 1 | <5 | |||
| 5 Sigmoid | 36.2 (5.0–55.0) | 1 | <5 | |||
| 6 Rectum | 17.1 (10.0–52.5) | 1 | <5 | |||
| 8 | 55 F | CC | 1 Descending | 16.8 (5.0–27.5) | 1 | 5–10 |
| 2 Sigmoid | 14.5 (7.5–37.5) | 1 | <5 | |||
| 3 Rectum | 15.4 (5.0–35.0) | 1 | <5 | |||
| 9 | 68 M | CC | Cecum | 26.3 (5.0–82.5) | 1 | <5 |
| 10 | 38 F | CC | 1 Ascending | 38.2 (7.5–100.0) | 1 | <5 |
| 2 Transverse | 25.8 (5.0–42.5) | 1 | <5 | |||
| 11 | 85 F | CC | 1 Colon | 35.0 (12.5–75.0) | 1 | <5 |
| 2 Colon | 24.3 (7.5–65.0) | 1 | <5 | |||
| 12 | 75 F | CC | 1 Rectosigmoid | 30.5 (12.5–137.5) | 1 | <5 |
| 2 Transverse | 20.8 (5.0–75.0) | 1 | <5 | |||
| 13 | 60 M | Adenoma | Colon* | 6.0 (2.5–12.5) | 0 | <5 |
| 14 | 68 M | Carcinoma | Colon* | 7.8 (2.5–12.5) | 0 | <5 |
| 15 | 84 M | Carcinoma | Colon* | 8.0 (2.5–12.5) | 0 | <5 |
| 16 | 74 M | Carcinoma | Colon* | 4.0 (1.5–7.5) | 0 | <5 |
| 17 | 64 M | Carcinoma | Colon* | 3.8 (1.5–5.0) | 0 | <5 |
| 18 | 40 F | Carcinoma | Colon* | 6.5 (2.5–10.0) | 0 | <5 |
| 19 | 73 M | Diverticulitis | Colon* | 7.5 (1.5–12.5) | 0 | <5 |
| 20 | 30 F | UC | Colon | 2.5 (1.5–5.0) | 2 | <5 |
| 21 | 40 F | UC | Colon | 3.0 (1.5–5.0) | 2–3 | <5 |
| 22 | 70 F | UC (rem.) | Colon | 1.5 (0.0–5.0) | 1 | <5 |
| 23 | 50 M | UC (rem.) | Colon | 2.0 (0.0–2.5) | 1 | <5 |
| 24 | 38 F | CD | Colon | 5.5 (1.5–7.5) | 2 | <5 |
| 25 | 26 F | CD | Colon | 2.5 (1.5–4.0) | 2 | <5 |
| 26 | 31 F | CD | Colon | 2.0 (1.5–2.5) | 2 | <5 |
| 27 | 64 M | CD | Colon | 2.2 (2.0–2.4) | 3 | <5 |
CC, collagenous colitis; UC, ulcerative colitis; UC (rem.), ulcerative colitis in remission; CD, Crohn’s disease; Colon*, mucosa distant to focal lesion; IEL, intraepithelial lymphocytes per 100 epithelial cells.
Inflammation: density of lymphoplasmocytic infiltrate graded as absent (0), mild (1), moderate (2), or severe (3).