Figure 1.

Microdissection of pulmonary tumorlet. Top: Premicrodissection. Bottom: Postmicrodissection. Microdissected areas range in size from 1 to 3 mm in greatest dimension. Normal pulmonary parenchyma was removed to serve as a internal negative control (open arrow). Note that the normal tissue sample for genotyping (open arrow) is similar in size to that of the tumorlet (solid arrow). Aggregate tissue was collected from up to four blank histological sections. Hematoxylin-eosin, magnification ×10.