Figure 5.
Immunohistochemistry of pancreatic cancer and dysplastic ducts in CP tissues. In the pancreatic cancer tissues (A-C) there was moderate to strong Id-1 (A), Id-2 (B), and Id-3 (C) immunoreactivity in the ductal cells in the areas adjacent to the cancer cells that exhibited CP-like alterations. Islet cells did not exhibit Id immunoreactivity (outlined by solid arrowheads). In the CP samples, moderate to strong Id-1 (D), Id-2 (E), and Id-3 (F) immunoreactivity was present in the cytoplasm of epithelial cells forming large dysplastic ducts. Scale bar, 25 μm.