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Age-dependent increase in EB22/5 expression in apoE-deficient mice by RPA. EB22/5 expression was not different at 3 months of age but was up-regulated beginning at 6 months of age in apoE-deficient mice compared to wild-type controls (WT). For each age time point n = 3, 3 months; n = 5, 6 months; n = 5, 8 months; n = 4, 9 months; n = 2, 15 months; n = 2, 24 months old mice. Statistical analysis was done by one-factor analysis of variance with post hoc Scheffé test, P < 0.05 (*).
