Table 1.

Effect of Complement on Phosphotyrosine Content of RTKs in GEC

RTK	Phosphotyrosine (% control)
EGF-R	204 ± 12*
Neu	384 ± 83†
FGF-R2	344 ± 153‡
Met	296 ± 61†

GEC were incubated with anti-GEC antibody and normal serum to form C5b-9, or with heat-inactivated serum in controls (as in Figure 1 ▶ ). Lysates were immunoprecipitated with antibodies to RTKs and immunoblotted with antibody to phosphotyrosine. Phosphotyrosine content was measured by densitometry.

*P < 0.0001,

^†P < 0.01,

^‡P = 0.05 versus control; each group consists of 3 to 4 experiments.