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Increased serum anti-fluorescein IgG after intratracheal FITC. A single dose of intratracheal FITC or PBS was administered to Balb-c or C57BL-6 mice. Mice were killed at day 21 and serum was assayed for fluorescein specific antibodies. Increased production of serum anti-fluorescein IgG was noted in both Balb-c and C57BL-6 mice. *P < 0.05 compared to same strain PBS control, unpaired t-test; n = 5–8 animals; representative data from seven experiments.
