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. 1999 Nov;155(5):1635–1649. doi: 10.1016/s0002-9440(10)65479-x

Figure 7.

Figure 7.

Effect of baboon anti-αGal on renal fibroblast production of TGF-β (A) and collagen (B) A: After 60 hours of incubation with anti-αGal (αGal) and anti-PAEC (PAEC), active TGF-β in culture supernatants was twofold higher as compared to incubation with αGal antibody-free normal rabbit γ-globulin (NRb) or anti-β3 integrin (Int. β3) (*P < 0.01), and significantly higher than incubation with baboon anti-αGal absorbed with rabbit erythrocytes (αGal/RbE) or anti-PAEC absorbed with rabbit erythrocytes (PAEC/RbE) (*P < 0.05). B: Incubatin with baboon anti-αGal (αGal) induced a 2.5-fold increase in collagen synthesis, as compared to normal rabbit γ-globulin (NRb) (*P < 0.01). Baboon anti-αGal absorbed with αGal/RbE and Int. β3 did not induce a comparable stimulation. Data represent the mean ± SE.