Table 2.

Immunostaining Scores for Collagen I and Fibronectin, Compared to Normal Skin from the Same Subject

	Collagen I (d7)	Collagen I (d80)	Fibronectin (d7)
M-placebo	−4* (SD 1)	−1 (SD 1.4)	+1.2* (SD 0.4)
M-estrogen	−1.4 (SD 0.5)	+0.8 (SD 1.2)	+3 (SD 0.7)
F-placebo	−3* (SD 0.7)	−0.8* (SD 1.3)	+1.8* (SD 0.8)
F-estrogen	−1.2 (SD 0.4)	+1.3 (SD 0.5)	+3.2 (SD 0.8)

All values represent means; n = 5 (d7) and n = 4 (d80); SD, standard deviation; * P < 0.05. M, male; F, female. There was no significant staining for fibronectin in any section at day 80.