Figure 3.

Effects of IL-13 on liver neutrophil accumulation (A and B), hepatocellular injury (C), and liver edema (D) in sham control mice and mice undergoing ischemia and 4 hours of reperfusion treated with saline (I/R) or IL-13 (I/R + IL-13). Liver neutrophil accumulation was determined by measuring liver myeloperoxidase (MPO) content (A), as well as by liver tissue neutrophil morphometrics (PMN/high power field; B). Hepatocellular injury was assessed by determining serum levels of alanine aminotransferase (ALT). Liver edema was quantitated by liver wet-to-dry weight ratios. Values represent mean ± SE with n = 10 per group.