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Anti-tumor effect of HeFi-1, a functional anti-CD30 antibody, in SCID/bg mice xenografted with ALCL cells. Mice were injected intraperitoneally with 10 μg of anti-CD30 antibody (HeFi-1) or mouse IgG1 in 0.2 ml of PBS, as a control, every other day for 10 days, for a total of 5 injections beginning on day 6 after tumor implantation. Tumor volumes in cm 3 are plotted at 0 to 27 days (mean ± SD).
