Table 1.
Group | Time | |||
---|---|---|---|---|
0 weeks | 4 weeks | 8 weeks | 12 weeks | |
1 (control) | 271 ± 3.6 | 289 ± 5.7 | 311 ± 6.0d | 332 ± 7.0d |
2 (0.8 mg of microspheres) | 292 ± 3.7e | 299 ± 4.9d | 330 ± 6.0d | 324 ± 12.9d |
3 (0.4 mg of microspheres) | 287 ± 4.1b | 313 ± 3.6d,e | 335 ± 10.2b,d | 347 ± 14.8d |
4 (0.2 mg of microspheres) | 285 ± 4.4 | 308 ± 8.6b,d | 340 ± 13.3a | 366 ± 7.6b,c,d |
5 (0.1 mg of microspheres) | 282 ± 5.2 | 307 ± 4.9b,d | 345 ± 6.0d,e | 360 ± 3.8b,d |
a,b,c: P < 0.05 vs. 0 weeks, group 1, and group 3, respectively.
d,e: P < 0.01 vs. 0 weeks and group 1, respectively.