Table 1.
Distribution of Tryptase-Positive Cells Showing CCR3 Expression in Different Tissues
| Tissue | No. of cells/field (×250) | |
|---|---|---|
| Tryptase+ | Tryptase+/CCR3+ | |
| Gut | ||
| Mucosa | 25.5 ± 1.5 | 4.4 ± 0.5 (17%) |
| Submucosa | 22.7 ± 3.1 | 19.7 ± 1.2 (87%) |
| Ulcerative colitis | 46.2 ± 9.8 | 30.2 ± 9.7 (65%) |
| Lung | 19.4 ± 4.0 | 2.8 ± 0.5 (14%) |
| Skin | ||
| Systemic sclerosis | 16.6 ± 4.3 | 13.0 ± 3.5 (72%) |
Cells were costained for tryptase and CCR3 as described in Methods. Mean values (±SE) of absolute numbers of cells staining for tryptase (tryptase+) or for both (tryptase+/CCR3+), found by counting five consecutive microscopic fields (×250) for each section, are reported in the first and second columns, respectively. Values in parentheses express percentages of tryptase+/CCR3+ versus tryptase+ cells found in every tissue.