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. 1999 Oct;155(4):1293–1302. doi: 10.1016/S0002-9440(10)65231-5

Figure 5.

Figure 5.

A and B: Control PVG.R8 cardiac allograft 7 days after transplantation to PVG.1U (C6−) recipient reconstituted with bone marrow from a PVG.1U (C6−) rat. Immunoperoxidase stains for ED1 demonstrate extensive perivascular macrophage infiltrates (A), but only moderate expression of P-selectin on endothelial cells and minimal platelet aggregation (B). Experimental PVG.R8 cardiac allograft 7 days after transplantation to PVG.1U (C6−) recipient reconstituted with bone marrow from a PVG.1U (C6+) rat (C-F). Immunoperoxidase stains for ED1 delineates extensive perivascular and interstitial macrophage infiltrates (C). Immunoperoxidase stains for P-selectin on a sequential section demonstrates expression on endothelial cells and several layers of aggregated platelets in vessels of all sizes at low power (D) and in a capillary (E) and large artery (F) at higher magnification.