Table 2.
Summary of Morphometric Studies
Controls 4 months | PHN 4 months | Controls 8 months | PHN 8 months | PHN +Lisinopril | PHN +Lacidipine | |
---|---|---|---|---|---|---|
Glomeruli with a normal tubule, % | 98.5 (96–99.5) | 81* (70–86) | 98 (98–99) | 32†‡ (31–39) | 95§ (45–98) | 47* (43–57) |
Glomeruli with an atrophic tubule, % | 1 (0–2) | 11* (8–20) | 0.5 (0–1.5) | 41†‡ (35–43) | 5* (2–32) | 34* (23–37) |
Atubular glomeruli, % | 0.5 (0–2.5) | 9* (8–11) | 0.5 (0–2) | 27†‡ (24–30) | 0§ (0–23) | 20* (19–20) |
Fractional interstitial volume, % | 12.5 (11–13) | 21* (20–23) | 9.5 (9–10.5) | 39†‡ (29–49) | 16*§ (11–30) | 26* (20–26) |
All data are expressed as median and interquartile range.
*P < 0.05 and †P < 0.01 versus controls at correspondent time.
‡P < 0.01 versus PHN 4 months; §P < 0.05 versus PHN 8 months.