Figure 1.

Lymphoid follicles with germinal centers are present in cervix from women with high-grade SIL. Immunohistochemistry on serial sections from a paraffin-embedded sample of high-grade SIL (HIV-negative) was performed with antibody against CD4 (a), CD20 (b), CD8 (c), CD68 (d); positively stained cells appear brown. The stromal-epithelial junction is marked with a dashed line. Serial but not adjacent sections were stained with antibodies against CD68 (e) and for DNA fragmentation (f). Photos taken with 10X (a–d) and 40X (e and f) objective. E, epithelium; S, stroma; G, endocervical gland.