Aggregates of CD8+ T cells are present in high-grade SIL from HIV+ women. Immunohistochemistry on serial sections from high-grade SIL (HIV-positive patient) was performed with antibodies against CD4, CD20, CD8, and CD68. The stromal-epithelial junction is marked with a dashed line. Photos taken at 10X objective magnification. E, epithelium; S, stroma.