Ovarian cyclicity in adjuvant-immunized (Sybill, Ito), pZP3(mac)-immunized (Harriette, Babs), and pZP3(hu)-immunized (Meenie, Eenie) macaques monitored until sacrifice. Each point indicates time of menstrual bleeding. Time of first immunization is indicated as day 0. Asterisk denotes surgical removal of one ovary.