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Presence of Anitschkow-like cells in valves from Lewis rats immunized with HMM from HCM. In addition to inflammatory cell infiltrates, cells with caterpillar nuclei morphology were observed (arrowheads). The Anitschkow-like cells shown in the figure are cut longitudinally and the condensed chromatin gives the appearance of a caterpillar. Cells with caterpillar nuclei were observed in valves from rats immunized with intact HCM, RCM, and HCM subfragments, and LMM peptides.
