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Lung DNA ladder during hyperoxia. Lung DNA from air-breathing wt mice (control) and hyperoxia-exposed mice (wt, CD40−/−, and CD40L−/−) for 72 hours. Enriched fragments of DNA extracts were electrophoresed on 1% agarose gel. Note the presence of DNA ladder indicating apoptosis in all strains of mice exposed to hyperoxia for 72 hours.
