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Model of cell division, differentiation and death in the colonic cript. F0 represents the stem cell compartment, F1, partly differentiated cells, and F2, fully differentiated cells. Numbers of cells in each compartment are given by N0, N1, N2 and N3. Proportions of cells dying, differentiating, and renewing are given by α1, α2, α3, etc. t0, t1 and t2 represent the times taken for these processes to occur.
