Table 2.
Clinicopathological Features of EBV-Positive and -Negative GCs
EBV-positive GCs (n = 21) | EBV-negative GCs (n = 56) | P value* | |
---|---|---|---|
Age (years) | 50.2 | 56.6 | 0.043 |
M:F ratio | 17:4 | 41:15 | >0.05 |
Location | |||
Antrum | 4 (19%) | 34 (60.7%) | 0.02 |
Body/cardia | 17 (81%) | 22 (39.3%) | |
Histology† | |||
WD | 0 | 3 (5.4%) | 0.019 |
MD | 5 (23.8%) | 17 (30.4%) | |
PD | 16 (76.2%) | 21 (37.5%) | |
SRC | 0 | 9 (16.1%) | |
MUC | 0 | 6 (10.7%) | |
LELC‡ | 9 (42.9%) | 0 | <0.001 |
*Age was compared using Student’s t test; histology was compared using chi-square test; the remainders, using two-tailed Fisher’s exact test.
†Gastric carcinoma was classified, on the basis of a modification of the World Health Organization’s classification system, as well differentiated (WD), moderately differentiated (MD), poorly differentiated (PD), signet ring cell carcinoma (SRC), or mucinous carcinoma (MUC).
‡Lymphoepithelioma-like carcinoma.