Table 5.
Expression of Cell Adhesion Molecules in Allografts
| Time after transplantation | bm1 → B/6 Allografts | bm12 → B/6 Allografts | B/c → B/6 Allografts | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 4 hours | 24 hours | 3 days | 7 days | 4 hours | 24 hours | 3 days | 7 days | 4 hours | 24 hours | 3 days | 7 days | |
| ICAM-1 | ||||||||||||
| No storage | − | + | + | + | − | + | + | + | − | + | + | + |
| 4-hour cold ischemia | + | + | + | + | + | + | + | + | + | + | + | + |
| VCAM-1 | ||||||||||||
| No storage | + | + | + | + | − | + | + | + | + | + | + | + |
| 4-hour cold ischemia | + | + | + | + | + | + | + | + | + | + | + | + |
| P-selectin | ||||||||||||
| No storage | − | − | − | − | − | − | − | − | − | − | − | − |
| 4-hour cold ischemia | − | − | − | − | − | − | − | − | − | − | − | − |
| E-selectin | ||||||||||||
| No storage | − | − | − | − | − | − | − | − | − | − | − | − |
| 4-hour cold ischemia | − | − | − | − | − | − | − | − | − | − | − | − |
Immunohistochemical staining of cell adhesion molecules was graded as: −, not present or focal weak staining; +, diffuse or strong staining. Three samples at 4 or 24 hours, or four samples at day 3 or day 7 were examined for each group. Details are described in Materials and Methods.