Table 2.
Lichen Sclerosus
| Patient no. | Age at diagnosis | Specimen number | Diagnosis* | γ-TCR rearrangement | HPV16 |
|---|---|---|---|---|---|
| 22 1 | 67 years | 39435/99 | LS early, lichenoid infiltrate, no LA | ;*>;0>† | ;*>;0>† |
| 39435/99 | LS early, lichenoid infiltrate, no LA | ;*>;0>† | ;*>;0>† | ||
| 2 | 62 years | 6009/00 | LS, hypertrophic, scant lichenoid infiltrate | − | − |
| 3 | 68 years | 109943/99 | LS, lichenoid infiltrate | ;*>;0>† | ;*>;0>† |
| 109943/99 | LS, lichenoid infiltrate | ;*>;0>† | ;*>;0>† | ||
| 4 | 62 years | 7822/00 | LS, lichenoid infiltrate | ;*>;0>† | − |
| 5 | 66 years | 117349/99 | LS, scant lichenoid infiltrate | − | ;*>;0>† |
| 117349/99 | LS, scant lichenoid infiltrate | − | ;*>;0>† | ||
| 6 | 64 years | 8693/99 | LS, hypertrophic, scant lichenoid infiltrate, no LA | − | + |
| 8694/99 | LS, hypertrophic, scant lichenoid infiltrate, no LA | − | ++ | ||
| 98280/00 | LS, hypertrophic, scant lichenoid infiltrate, no LA | − | +++ | ||
| 98280/00 | LS, hypertrophic, scant lichenoid infiltrate, no LA | − | +++ | ||
| 98280/00 | LS, hypertrophic, scant lichenoid infiltrate, no LA | − | ++ | ||
| 7 | 66 years | 118700/99 | LS, dense lichenoid infiltrate | + | − |
| 8 | 66 years | 120030/00 | LS, hypertrophic, dense lichenoid infiltrate | +++ | − |
| 120031/00 | LS, hypertrophic, dense lichenoid infiltrate | − | + | ||
| 120032/00 | LS, scant lichenoid infiltrate | − | − | ||
| 9 | 58 years | 77667/99 | LS, lichenoid infiltrate, no LA | + | + |
| 77668/99 | LS, lichenoid infiltrate, no LA | + | + | ||
| 10 | 59 years | 67714/01 | LS, atrophic, scant infiltrate | − | − |
| 11 | 85 years | 89087/98 | LS, atrophic, scant infiltrate | − | − |
| 89087/98 | LS, atrophic, scant infiltrate | − | + | ||
| 89087/98 | LS, atrophic, scant infiltrate | − | + | ||
| 89087/98 | LS, atrophic, scant infiltrate | − | − | ||
| 89087/98 | LS, atrophic, scant infiltrate | − | − | ||
| 89088/98 | LS, atrophic, scant infiltrate | − | − | ||
| 89088/98 | LS, atrophic, scant infiltrate | − | − | ||
| 89089/98 | LS, atrophic, scant infiltrate | +++ | − | ||
| 12 | 60 years | 123682/00 | LS, dense lichenoid infiltrate | − | − |
| 123682/00 | LS scant lichenoid infiltrate, LA | + | + | ||
| 13 | 35 years | 61892/01 | LS, dense lichenoid infiltrate | ;*>;0>† | ;*>;0>† |
| 61893/01 | LS, dense lichenoid infiltrate | ;*>;0>† | ;*>;0>† | ||
| 14 | 86 years | 38349/98 | LS, atrophic, scant infiltrate | − | − |
| 38350/98 | LS, no lichenoid infiltrate, LA | + | + | ||
| 38350/98 | LS, atrophic, scant infiltrate | − | − | ||
| 111742/98 | LS, hypertrophic, scant lichenoid infiltrate, no LA | − | + | ||
| 111742/98 | LS, hypertrophic, scant lichenoid infiltrate, no LA | − | + | ||
| 15 | 36 years | 43056/01 | LS, atrophic, scant lichenoid infiltrate | − | − |
| 16 | 70 years | 95974/00 | LS, atrophic, scant infiltrate | + | + |
| 95975/00 | LS, atrophic, scant infiltrate | + | +++ | ||
| 17 | 76 years | 75547/00 | LS, atrophic, scant infiltrate | ;*>;0>† | ++ |
| 75548/00 | LS, atrophic, scant infiltrate | ;*>;0>† | − | ||
| 18 | 87 years | 34633/00 | LS, dense lichenoid infiltrate | ;*>;0>† | + |
| 34634/00 | LS, dense lichenoid infiltrate | ;*>;0>† | ++ | ||
| 19 | 60 years | 3423/01 | LS, atrophic, scant infiltrate | − | − |
| 3424/01 | LS, atrophic, scant infiltrate | − | − | ||
| 20 | 61 years | 81076/01 | LS, hypertrophic, lichenoid infiltrate | + | − |
| 21 | 89 years | 30665/99 | LS atrophic, no lichenoid infiltrate, LA | +++ | − |
| 30666/99 | LS, atrophic, no infiltrate, LA | − | − | ||
| 22 | 61 years | 24409/00 | LS, hypertrophic, scant lichenoid infiltrate | − | − |
* Each lane represents a different paraffin-embedded tissue block.
† Poor DNA-quality.
+, One of three separately obtained and analyzed samples; ++, two of three separately obtained and analyzed samples; +++, three of three separately obtained and analyzed samples.
−, Negative; +, positive. LS, lichen sclerosus; LA, lymphocytic aggregate.