Table 1.
Body Weights, Relative Weights of Kidneys and Left Ventricles, Creatinine Clearance, and Albumin Excretion of All Experimental Groups
| Body weight, g | Relative kidney weight, mg/g | Relative weight of left ventricle, mg/g | Creatinine clearance, ml/min | Albumin excretion, mg/day | |
|---|---|---|---|---|---|
| Wild type | 25.5 ± 1.6 | 10.9 ± 1.2 | 4.4 ± 0.3 | 0.43 ± 0.1 | 0.4 ± 0.2 |
| Wild type/DOCA | 23.8 ± 1.3 | 14.2 ± 1.3* | 5.5 ± 0.2* | 0.19 ± 0.02* | 3.3 ± 1.4* |
| α8−/− | 24.4 ± 0.4 | 9.9 ± 0.3 | 4.2 ± 0.2 | 0.30 ± 0.03 | 0.2 ± 0.1 |
| α8−/−/DOCA | 20.9 ± 0.5* | 14.4 ± 0.6* | 5.8 ± 0.2* | 0.17 ± 0.03* | 3.1 ± 0.9* |
Data are means ± SEM.
*P <0.05 DOCA-treated mice versus controls.