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Vascular permeability in ischemia-reperfused skeletal muscle. Vascular permeability in vivo was evaluated by measuring extravasation of tracer EBD. Shown is a ratio of EBD extravasation in ischemic limb to that in non-ischemic limb in WT (open bar), eNOS-Tg mice (solid bar), and L-NAME-treated eNOS-Tg mice (hatched bar). n = 5 to 9 for each group. *P <0.05 vs. WT and L-NAME-treated eNOS-Tg mice at 60 minutes after reperfusion.
