Table 1.
ASPS case* | Age, sex | Primary site | ASPL-TFE3 fusion type | PASD granules | MCT1 immunostaining | CD147 immunostaining | ||||
---|---|---|---|---|---|---|---|---|---|---|
Membrane staining | Cytoplasmic staining | Membrane staining | Cytoplasmic staining | |||||||
Diffuse | Discrete granules | Diffuse | Discrete granules | |||||||
1 | 19 F | Thigh | 1 | ++ | ++ | − | +++ | ++ | + | ++ |
2 | 36 F | Axilla | 2 | ++ | + | − | +++ | − | + | ++ |
3 | 31 F | Thigh | 1 | + | +f | − | − | +f | + | + |
4 | 38 M | Arm | 2 | +++ | +f | + | +++ | − | + | ++ |
5 | 29 F | Thigh | 1 | ++ | + | + | + rare | ++ | + | + |
7 | 40 F | Thigh | 1 | ++ | +f | − | − | +f | − | − |
14 | 36 F | Thigh | 1 | ++ | + | − | ++ | ++ | + | + |
15 | 41 M | Shoulder | ;*>;0>† | − | +f | ++ | − | − | + | + |
16 | 36 F | Thigh | n.a. | +++ | ++ | + | +++ | + | ++ | ++ |
17 | 21 F | Thigh | ;*>;b>‡ | + | ++ | − | + rare | − | − | − |
+, few; ++, moderate; +++, many; f, focal; n.a., not available.
*Unique case numbers from serial collection of ASPS samples.
†TFE3 genomic rearrangement demonstrated by Southern blot analysis (see text). No RNA available for reverse-transcriptase-polymerase chain reaction.
‡Cytogenetic evidence of t(X;17) (see text). No RNA available for reverse-transcriptase-polymerase chain reaction.