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. 2002 Apr;160(4):1507–1520. doi: 10.1016/S0002-9440(10)62577-1

Figure 7.

Figure 7.

Cathepsin B and apoptosis. Percentage of apoptotic cells at 24 hours (double-staining annexin V/propidium iodide) and at 48 hours (by TUNEL reaction) after cisPt treatment in both 8863 (A) and 1B6 (B) cell lines pretreated with cystatin C as specific inhibitor of cathepsin B. Cystatin C exerted only a partial protection in 1B6 cells after 24 hours of cisPt treatment. By contrast, a significant protective effect was detected in 8863 cells at both 24 and 48 hours after cisPt treatment.