Table 2.

Significance of Strong NCAM Expression by Immunohistochemistry in Distinguishing MM from Other B-Cell Neoplasms and in Predicting Lytic Bone Lesions

	Chi-square	P value	Odds ratio
MM versus polyclonal plasmacytosis	114.05	<0.0001	inf.
MM versus MGUS	56.47	<0.000	33.2
MM versus plasmacytoid non-Hodgkin’s lymphomas	92.30	<0.000	inf.
MM with lytic lesions versus MM without lytic lesions	33.39	<0.000	16.9
PPV for lytic lesions	90%
NPV for lytic lesions	65%
Sensitivity for lytic lesions in MM patients	91%
Specificity for lytic lesions in MM patients	63%

PPV, positive predictive value; NPV, negative predictive value.