Table 1.
Telomere Length Comparison by TELI-FISH: Matched Normal Prostate Epithelium versus Prostate Cancer
| Case | Gleason score | Stage | Normal mean | SD | n | Tumor mean | SD | n | Delta (normal-tumor) | P value |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 6 | T2N0Mx | 672 | 439 | 13 | 180 | 101 | 10 | 492 | .0019* |
| 2 | 6 | T2N0Mx | 216 | 98 | 13 | 104 | 45 | 14 | 112 | .0016* |
| 3 | 7 | T2N0Mx | 443 | 234 | 10 | 185 | 93 | 9 | 259 | .0073* |
| 4 | 7 | T3aN0Mx | 278 | 78 | 6 | 160 | 70 | 12 | 118 | .0046* |
| 5 | 7 | T2N0Mx | 415 | 121 | 13 | 238 | 103 | 12 | 176 | .0007* |
| 6 | 6 | T2N0Mx | 372 | 83 | 18 | 243 | 109 | 16 | 129 | .0005* |
| 7 | 6 | T2N0Mx | 258 | 165 | 13 | 109 | 34 | 23 | 149 | .0002* |
| 8 | 7 | T2N0Mx | 363 | 148 | 10 | 58 | 30 | 10 | 305 | <.0001* |
| 9 | 7 | T2N0Mx | 141 | 49 | 12 | 40 | 34 | 13 | 101 | <.0001* |
| 10 | 6 | T2N0Mx | 388 | 107 | 16 | 178 | 69 | 17 | 210 | <.0001* |
| 11 | 7 | T3aN0Mx | 167 | 92 | 13 | 124 | 70 | 10 | 43 | .232 |
| 12 | 7 | T2N0Mx | 188 | 142 | 11 | 115 | 71 | 12 | 73 | .14 |
| 13 | 6 | T2N0Mx | 356 | 267 | 9 | 175 | 219 | 9 | 182 | .14 |
| 14 | 6 | T3aN0Mx | 318 | 166 | 8 | 288 | 301 | 6 | 31 | .81 |
| 15 | 7 | T2N0Mx | 70 | 48 | 11 | 67 | 26 | 11 | 4 | .83 |
| 16 | 6 | T2N0Mx | 170 | 102 | 12 | 321 | 176 | 15 | −151 | .0143* |
| 17 | 6 | T2N0Mx | 137 | 56 | 9 | 408 | 201 | 17 | −270 | <.0001* |
* Indicates statistically significant difference between tumor and normal. n indicates the number of individual cell nuclei used for each sample (ie, tumor or normal).