Table 1.
Marker | Chromosomal location | Repeat type | Putative tumor suppressor gene(s)/remarks |
---|---|---|---|
D2S123 | 2p16-21 | Dinucleotide | hMSH2; MSI consensus marker |
D3S1478 | 3p21 | Dinucleotide | FHIT; hMLH1 |
D3S2456 | 3p | Tetranucleotide | FHIT; hMLH1 |
D5S346 | 5q21 | Dinucleotide | APC; MSI consensus marker |
D5S107 | 5q11.2-q13.3 | Dinucleotide | APC |
D9S171 | 9p21 | Dinucleotide | p14ARF; p16INK4A; p15INK4B |
D9S932 | 9p | Tetranucleotide | p14ARF; p16INK4A; p15INK4B |
D10S2491 | 10q23 | Dinucleotide | PTEN (intragenic marker) |
D14S68 | 14q24.3-q | Dinucleotide | frequently deleted region in Barrett carcinomas |
D16S2624 | 16q22.1 | Tetranucleotide | E-cadherin |
P53 Alu | 17p | Alu repeat | p53 (intragenic marker) |
TP53 | 17p13.1 | Dinucleotide | p53 |
D17S250 | 17q11.2-q12 | Dinucleotide | BRCA1; MSI consensus marker |
D18S64 | 18q21.32 | Dinucleotide | DCC; DPC4/SMAD4; SMAD2 |
D18S474 | 18q | Dinucleotide | DCC; DPC4/SMAD4; SMAD2 |
D19S565 | 19p13.3 | Dinucleotide | STK11/LKB1 |
D19S886 | 19p13.3 | Dinucleotide | STK11/LKB1 |
D21S49 | 21q22.3 | Dinucleotide | TFF1 |
BAT25 | 4q12 | Mononucleotide | MSI consensus marker |
BAT26 | 2p16 | Mononucleotide | MSI consensus marker |
BAT40 | 1p13.1 | Mononucleotide | MSI consensus marker |