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. 2002 Oct;161(4):1207–1213. doi: 10.1016/S0002-9440(10)64397-0

Table 1.

Markers for LOH and MSI Analysis

Marker Chromosomal location Repeat type Putative tumor suppressor gene(s)/remarks
D2S123 2p16-21 Dinucleotide hMSH2; MSI consensus marker
D3S1478 3p21 Dinucleotide FHIT; hMLH1
D3S2456 3p Tetranucleotide FHIT; hMLH1
D5S346 5q21 Dinucleotide APC; MSI consensus marker
D5S107 5q11.2-q13.3 Dinucleotide APC
D9S171 9p21 Dinucleotide p14ARF; p16INK4A; p15INK4B
D9S932 9p Tetranucleotide p14ARF; p16INK4A; p15INK4B
D10S2491 10q23 Dinucleotide PTEN (intragenic marker)
D14S68 14q24.3-q Dinucleotide frequently deleted region in Barrett carcinomas
D16S2624 16q22.1 Tetranucleotide E-cadherin
P53 Alu 17p Alu repeat p53 (intragenic marker)
TP53 17p13.1 Dinucleotide p53
D17S250 17q11.2-q12 Dinucleotide BRCA1; MSI consensus marker
D18S64 18q21.32 Dinucleotide DCC; DPC4/SMAD4; SMAD2
D18S474 18q Dinucleotide DCC; DPC4/SMAD4; SMAD2
D19S565 19p13.3 Dinucleotide STK11/LKB1
D19S886 19p13.3 Dinucleotide STK11/LKB1
D21S49 21q22.3 Dinucleotide TFF1
BAT25 4q12 Mononucleotide MSI consensus marker
BAT26 2p16 Mononucleotide MSI consensus marker
BAT40 1p13.1 Mononucleotide MSI consensus marker