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Frequency of LOH on Chromosome 6 According to Masaoka’s Stage
| Stage | Genetic aberration frequency (%) |
|---|---|
| I | 25/357 (7.0%) |
| II | 152/573 (26.5%) |
| III | 87/407 (21.4%) |
| IV | 69/287 (24.0%) |
A significant difference (chi-square-test) was found between stages I (noninvasive thymoma) and II to IV (invasive thymoma) (P < 0.0001).
