. 2002 Oct;161(4):1497–1505. doi: 10.1016/s0002-9440(10)64425-2

Table 1.

Gliotoxin Treatment Reduces Pathological Changes in Anti-Thy 1.1 Glomerulonephritis

Day	Glomerular lesions				ED1+ cells
		Control		Nephritis		Control		Nephritis
	Saline	Gliotoxin	Saline	Gliotoxin	Saline	Gliotoxin	Saline	Gliotoxin
2	0.5 ± 0.1	ND	1.3 ± 0.3^†	0.5 ± 0.3^*^‡	0.9 ± 0.1	ND	6.0 ± 1.4^†	3.0 ± 0.7^*^‡
4	0.8 ± 0.1	0.3 ± 0.2^*	2.2 ± 0.5^†	1.0 ± 0.2^*^‡	0.9 ± 0.1	1.1 ± 0.6^*	7.9 ± 1.8^†	2.5 ± 0.7^*^‡
7	0.5 ± 0.1	ND	2.9 ± 0.2^†	1.0 ± 0.1^*^‡	0.9 ± 0.1	ND	9.5 ± 2.0^†	2.0 ± 0.1^*^‡
10	0.3 ± 0.2	0.4 ± 0.2^*	2.0 ± 0.5^†	1.0 ± 0.1^†^‡	1.1 ± 0.3	0.9 ± 0.1^*	5.6 ± 1.7^†	0.8 ± 0.6^*^‡

Glomerular damage was scored from 0 to 3. Infiltrating monocytes/macrophages were expressed as number of ED1+ cells/glomerular cross section (gcs). Values are mean ± SD.

*^†, Not significant and P < 0.05 compared to control rats receiving saline, respectively.

^‡P < 0.05 versus untreated nephritis rats (injected with saline). ND, not determined.