Figure 2.

Effect of sodium orthovanadate on tyrosine phosphoproteins. Lysates from SU-DHL-1 cells treated (+) or untreated (−) with sodium orthovanadate were immunoprecipitated and probed with the 4G10 anti-phosphotyrosine antibody. The lane corresponding to sodium orthovanadate-treated cells illustrates a total of 16 immunoreactive bands ranging from 130 through 8 kd. The lane corresponding to untreated cells illustrates a total of nine immunoreactive bands ranging from 130 through 8 kd. Densitometry analysis of the band corresponding to NPM-ALK, denoted by arrows, demonstrated an 18% increase in band intensity in the lane corresponding to sodium orthovanadate-treated cells.