Table 1.
MGB1 | SBEM | PDEF | |
---|---|---|---|
SAGE database* | |||
Normal tissues | 9:2 | 376:0 | 4:0 |
Cancer tissues | 17:4 | 32:0 | 126:0 |
Reported description | |||
Tissue-specific expression | Yes | Yes | Yes |
Expressing organ(s) | Breast† | Breast and salivary glands | Breast and prostate |
Expression in breast cancers | Yes | Yes | Yes |
References | 11, 16 | 14 | 12, 13 |
RT-PCR | |||
Primary breast cancer (n = 22)‡ | 22 | 20 | 20 |
Normal lung (n = 22) | 0 | 21 | 20 |
Ratio of total breast counts to lung counts; libraries used were GSM692, 677, 691, 760, and 780 for normal breast tissue; GSM 670, 671, 672, 673, and 694 for breast cancer tissue, and GSM762 for normal lung tissue.
One article reported low-level of expression in gynecological malignancies, using nested RT-PCR.
All are invasive ductal carcinoma.