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. 2005 May;7(2):160–170. doi: 10.1016/S1525-1578(10)60542-9

Table 1.

Patient Characteristics

Patients
Carcinoma and Adenoma
MS-status manually dissected MMR proteins
Laser dissected lesion Microsatellite loci
No. F/M YS Type* Location** CA-stage AD-size CA-grade AD-dyspl. MSH2 MLH1 MSH6 BAT40 BAT25 BAT26 APC D2S123 Mfd15
1 F 30 CA T T3N1MX 2 MSI-H + − + nd + + − + −
tAD 2 cm 0.5 cm D3 MSI-H + − + nd + + + + −
MSI-H D1 + + + + + −
MSI-H D2 + + + − − +
MSI-H D3 + + + + + −
2 F 49 CA T T3N0M0 2 MSI-H − + (+) nd + + + + −
tvAD 5 cm 1.5 cm D3 MSI-H − + (+) nd + + + − +
MSI-H D1 + + + − − +
MSI-H D2 + + + + − +
MSI-H D3 + + + + − +
3 F 56 CA END T1N0M0 2 MSI-H − + (+) nd − + + − +
tADm S 1 cm D3 MSI-H − + (+) nd + + + + +
MSI-H D1 + + + + + +
MSI-H D2 + + + + + +
MSI-H D3 + + + + + +
4 M 46 CA T T3N0M0 2 MSI-H + − + nd + + + + +
tvAD 2 cm 1.5 cm D3 MSI-H + − + nd + + + nd +
MSI-H D2 + + + + + +
MSI-H D3 + + + + + +
5 F 78 CA S T3N1MX 3 MSI-H − + − nd + + + + +
tAD 2 cm 0.8 cm D3 MSI-H − + − nd + + + + +
MSI-H D2 + + + + + +
MSI-H D3 + + + + + +
6 F 63 CA T T2N0MX 2 MSI-H + − + nd + + nd + +
tAD adj. 0.8 cm D3 MSI-H + − + nd + + − + +
MSI-H D2 − + + + + +
MSI-H D3 − + + + − +
7 M 43 CA A T3N2MX 3 MSI-H − + (+) nd + + + nd +
tAD 4 cm 0.5 cm D1 MSI-H − + (+) nd + + + − +
MSI-H D1 − + + + − +
8 M 40 CA in R T1N1M0 2 MSI-H − + − pT1 + + + + + +
tvAD 2.5 cm D2 MSI-H (+) + (+) nd + + − + +
MSI-H + D1 − + + − + −
MSI-H + D2 + + + − + −
MSI-H − D1 − + + + + +
MSI-H − D2 − + + + + +
9 F 39 CA T T4N2MX 2 MSI-H + − + nd + + − + +
tAD 6 cm 1.5 cm D2 MSI-L + − + nd − + − − −
MSI-H D1 − − + + + −
MSI-H D2 − + + + − +
10 F 35 CA R T2N0M0 2 MSI-H + − + nd + + + + +
tAD 1 cm 0.4 cm D1 MSI-L + − + nd − − − − +
MSI-H D1 + − + + − −
MSI-H D2 + − + + − +
11 M 44 CA A T2N0MX 2 MSI-H + − + nd + + + + +
tvAD 6 cm 1.5 cm D2 MSS + − + nd − − − − −
MSI-H D1 + + − − − +
MSI-H D2 + − − + − −
12 M 50 CA S T3N0M0 2 MSI-H − + − nd + + − + nd
tAD 8 cm 0.5 cm D2 MSS − + − nd − − − − −
MSI-L D1 + − − − − −
MSI-H D2 + − − − − +
13 M 24 CA in R T1N1M0 2–3 MSI-H − + (+) pT1 + + + + − +
fAD 3.5 cm D3 MSS − + (+) − (+) − − − −
MSI-L D1 − − + − − −
MSI-L D2 − + − + − −
MSI-H D3 + + − + − −
14 F 44 CA in T T1N0M0 3 MSI-H + − + pT1 + + + + + +
fAD 4 cm D3 MSS + − + nd − − − − −
MSI-H D3 + + + + + +
15 M 41 CA in R T1N0MX 2 MSI-H + + + pT1 + − − + − +
fAD 1.0 cm D3 MSS + + + nd − − − − −
MSS D1 − − − − − −
MSS D2 − − − − − −
MSI-L D3 − − − − − +
16 M 55 CA A T3N0M0 2 MSI-H − + − nd + + + + +
tAD 3 cm 0.7 cm D1 MSS + + + nd − − − − −
MSS D1 − − − − − −
17 M 42 CA A T3N0M0 3 MSI-H + − + nd + + + + +
tvADm R 2 cm D3 MSI-H + − + nd + + + + +
MSI-H + − + nd + + + + +
tADm R 0.8 cm D2 MSS + + + nd − − − − −
MSS D1 − − − − − −
MSS D2 − − − − − −

The patients identification number (No.), sex (F/M), age at diagnosis of the cancer (YS) are listed in the first column (patients). In the second column (carcinoma and adenoma) data of tumor type (AC, adenocarcinoma; AD, adenoma), localization of the tumor (A; ascending colon; T; transverse colon; S; sigmoid colon; R; rectum; END; endometrium; adj.; adjacent to carcinoma) tumor stage, and grade are presented. In the second row the data are given for the syn- or metachronous adenomas including adenoma type (t; tubulous; tv; tubulovillous; f; flat), the distance to a synchronous cancer (if applicable [cm]) and size of the lesion (maximum diameter, [cm]) as well as the grading (D1; mild dysplasia; D2; moderate dysplasia; D3; severe dysplasia). In the third column (MS status) results of the MSI analysis are listed with MS status after manual dissection being underlined. In the fourth column (MMR proteins) staining results of MSH2, MLH1, and MSH6 are shown. In the fifth column (laser) the different grades of dysplasia which were collected by laser microdissection are presented. The last column (microsatellite loci) lists data of the MSI analysis for each single locus.