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. 2005 Aug;7(3):337–345. doi: 10.1016/s1525-1578(10)60562-4

Figure 2.

Figure 2

Analysis of the P values arising from 16,733 t-tests as a β-uniform mixture. Top left: Histogram of the observed P values, with overlaid curves representing the division into uniform and β contributions. Top right: Relationship between cutoff for P values and the false discovery rate. Bottom left: Relation between cutoff for P values and the posterior probability of differential expression. Bottom right: Receiver operating characteristics curve associated with selecting different P value cutoffs.