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ROC curves of a 9p21, 8q24.12-13, 17q11.2, and 20q13.2 probe combination for the detection of combined high-grade dysplasia and esophageal adenocarcinoma relative to the lower diagnoses of low-grade dysplasia, intestinal metaplasia, and normal squamous epithelium (filled circles), and detection of low-grade dysplasia relative to the combined diagnoses of intestinal metaplasia and normal squamous epithelium (open circles).
