Table 3.
Results of Student’s t-tests Performed on Fluorescence Intensity Ratios of BAC Clones at the Same State (1-Copy Loss, 1-Copy Gain, Normal) from Cell Lines of the Same Ploidy
| Ploidy | Copy number state | Cell line | Mean ratio value (n) | P value |
|---|---|---|---|---|
| Diploid | 1-Copy loss | C4I | 0.8164 (85) | 0.15 |
| C4II | 0.7086 (90) | |||
| Normal copies | C4I | 1.0156 (410) | 0.21 | |
| C4II | 1.0067 (478) | |||
| 1-Copy gain | C4I | 1.3370 (23) | 0.99 | |
| C4II | 1.3366 (116) | |||
| Triploid | 1-Copy loss | ME180 | 0.7847 (207) | 0.16 |
| SiHa | 0.7777 (281) | |||
| Normal copies | ME180 | 1.0279 (189) | 0.067 | |
| SiHa | 1.0081 (349) | |||
| 1-Copy gain | ME180 | 1.2762 (75) | 0.070 | |
| SiHa | 1.2403 (77) |
No significant difference between ratio values was detected (P > 0.05). Ratio values of clones at the same state within each ploidy were therefore pooled in downstream analyses.