Figure 3.

 Effect of chronic ingestion of diets with varying nutrient composition in healthy volunteers. Following ingestion of a diet low in carbohydrate content (10%) and high in fat content (40%) for four weeks, postprandial enzyme output was about twice as high as following a high carbohydrate (80%), low fat (10%) diet (geometric means, ANOVA: *p<0.05). Interdigestive pancreatic enzyme output was about four times higher with the low carbohydrate, high fat diet. Thus, chronic ingestion of a high fat diet is associated with higher enzyme outputs than a carbohydrate rich diet.²⁴